Kálium sók értágító hatásukat a nitrogén-monoxid növelésével érik el vagy teljesen más mechanizmussal?

"Two targets of external potassium ions have been proposed: the Na+/K+ ATPase and the inward rectifier potassium channel.159 An elevation of external potassium causes very different responses of these two molecular targets. The electrogenic Na+/K+ ATPase is activated by external potassium with a half-activation constant of about 1 to 2 mmol/L10 and saturation above 5 mmol/L.1112 Activation of the Na+/K+ ATPase by elevating external potassium from nominally 0 to 5 mmol/L causes transient hyperpolarization and dilation ; the transient nature presumably reflects the extrusion of sodium until a new steady state is reached. In contrast, elevation of external potassium causes a graded shift in the apparent voltage-dependence of the inward rectifier potassium channel conductance, which can lead to a maintained hyperpolarization and dilation"

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